The Experimental Ketamine Cure for Depression


100 comments

  1. The FDA hasn't approved ketamine for psychiatric disorders — but that isn't stopping "off-label" treatment clinics from opening up all around the country.

    WATCH NEXT: The Cuban Punks Who Infected Themselves with HIV in Protest — http://bit.ly/2kXEa2N

  2. Dear doc I’m gonna pay you for putting me in a K hole….. am I cured yet?

    Dear patient not until I pay off my second house…

  3. This treatment saved me. I didn't realize how really, really down and desperate I was. I knew I'd been depressed for basically my whole life. After the first treatment (I've had 6) I felt like a new person. I was a lighter, less weighted, less dread, less doom person. I actually have been waking up on m own, early, and not forcing myself back to sleep to escape. This one aspect, in and of itself, is amazing to me.

  4. the host seems like a moron..but other than that…it was interesting research..as i was curious how this particular drug was used to treat depression…

  5. Thanks for making this video y'all! This will definitely help me write my 10 page paper on the medicinal use of ketamine for treatment resistant depression.

  6. I was in two clinical drug trials for Ketamine for treatment-resistant depression and I can tell anyone, it works! I did the I.V. and the nasal inhaled trials.

  7. “i may not be safe or effective for a long period of time”
    well, neither as prescription drugs, my brain is fucked from antipsychotic’s and antidepressants.

  8. Wish I could afford this treatment. I'm only a half hour away from this facility and suffer from treatment resistant depression. Taken every pill under the sun and if one more fucking psychologist tells me to take a long walk and appreciate the surroundings i'm gonna punch him/her in the face.

  9. Everyone who thinks theyre anti-drug just isn't once they need to save a family member with it. I'll dose my own kids if they start attempting suicide, shiiiit

  10. What he said about watching a movie of your life from an outside, objective point of view when you're on Ketamine is so true.

    The last time I used any drug was a Ketamine analog called Deschloroketamine (DCK) over a year ago. I'm an alcoholic and a drug addict and it was a relapse. I had ordered drugs online and wandered off on a walk, away from my parents house and into the woods to go use them. The problem was for some reason, I had mixed up the amount of time a Ketamine trip takes with Nitrous….. I've used a lot of drugs in my life and never made a serious error in judgement like that before. So anyway, after awhile, I realized my mistake and that I wasn't going to be able to go home, because I was obviously tripping. Then my phone died.

    Long story short, my parents basically thought I had fallen off of a cliff in the woods and died. But seeing my life, my drug use, my recovery progression from an outside point of view was absolutely incredible. I remember saying over and over again, "I'm so fucked". It was extremely powerful. I credit my year in sobriety now to my strong support network within AA, friends, and family but I like to think that the fact that I had used Ketamine as my "last use", had something to do with it as well. It just gave me a whole new perspective.

  11. Cardio,going to the gym in general, mindfullness and understanding the physcology and bioligical reasons will make you alot better not taking ketamine this is such a far left treatment bet uni students love this😂

  12. I no there are no words that i can say to show how thankful i am to see the people trying this drug.. being a lab rat would not be fun. I may need ketamine in the days ahead but very scared to get it.. i wanna be sure that its safe long term. I don't want to be a pussy but i would rather die than forget everything and lose my mind, of course i already feel that way.. but thanks everyone it truly means so much to me. You people are very brave i no depression isn't fun i had it six months straight now and i couldnt imagin staying in that pain for as long as some of you.. i tempted suicide and was just put on paxil i hope it works for me.. God is looking out for us people. Also thanks for the researchers doing great testing..

  13. I couldn’t hear a lot of the conversations..because of I’m deaf
    Side note: I’m going to hell anyway

  14. I genuinely think that is curing his depression because its giving him something to look forward to

  15. I was stabbed in the neck some years ago, and so since then i get spells of anxiety and feeling associated with anxiety. It must be PTSD. Right Doc? So Dr. Feelgood I think can certainly benfit from the same ketamine treatmine that my buddy here just got. Do you agree dr.? Of course my son, you too can experience a better life through chemistry

  16. I have suffered with depression since I was 13 and now 32. Two years ago after I had a nervous breakdown I was diagnosed bipolar and PTSD. Lamictal was a life saver but after two years on it, I see it's starting to not help as it did. I see therapist and he doesn't help. He ask if I'm taking my meds and listens to what I have to say but never offers anymore help! They say this can cause long term affects on the brain. Coming from someone who struggles when it comes to how I think. We don't care about the long term affects because we are just trying to survive day to day! Just know you are not alone! I'm so sorry we suffer from this disease and pray for help!

  17. Of course the FDA won’t approve it b/c it actually works. Instead, let’s give you a shit ton of psych meds so Big Pharma can make a pretty penny. Then, those synthetic meds will give you side effects, and you’ll need more scripts. It’s insane how many people who are initially prescribed one medication are then given numerous scripts, and you come to a point when you’re just treating side effects to meds. It’s a vicious cycle.

  18. $450 per ketamine infusion!?!?!?! Wtf!?!? Some of it covered though right? LMFAO, and drug dealers are the criminals eh? SMH sad af really

  19. A bunch of Coca-Cola will try your brain. The repair of the synapse and dendrites interested sign me up. Chronic depression daily.

  20. The journalist is clueless. He didn't need it but did it to see how it felt. His experience is not like the experience of someone who has real depression or real PTSD.

  21. If depression kept me down for YEARS and didn't do anything important because of it and then all of sudden I didn't feel that way I would probably feel a degree of rage, not relief. Rage at someone who was responsible for this unnecessary emotional pain and humiliation that comes with depression.
    There is no way to win once you are cursed with this horrible disease.

  22. I have been depressed and feeling worthless for SO LONG that I would not know how to handle success and the pleasure it would bring.
    It would most likely freak me out since, to me, it's not normal to feel good most of the time.
    I feel like the more successful you are in life the better the chance that you will be damned in the afterlife.
    I might be interpreting things wrong but I feel that way.

  23. This could turn into a "if you want your pleasure then line up and do as we say and pay up".
    This treatment could seriously turn into a horrible master/slave situation.

  24. The medical industry has a GOLD MINE in not curing or giving a concrete treatment for depression. The suffering of millions on ineffective, yet profitable anti-depressants would be undercut from any treatment that is simple and once a month.
    The system is more corrupt than you think. If you are weak and mentally unstable, God help you – they will crush and destroy your personality.
    It's almost as bad as the 1800s but in pill form.

  25. After watching this video i feel comfortable in saying that, as an Earth Born human being, having lived in 3 continents of the world throughout my life, I would honestly say that, beyond a shadow of a doubt, while also not intending to hurt anyones feelings or ruin anyones day just by commenting, and while still remembering that so many lives have been lost throughout history that were directly related to this subject, and also trying to be completely objective while still offering insight into the situation, I truly think that, even if you don't personally agree with me, and keeping in line with the narrative of this video, that i forgot what i was going to say.

  26. I got anxiety and depression.only realized after 5 months struggling. I feel useless, afraid of the dark, difficult to breath that led me to get out from the house to get oxygen, i throw all my ciggarettes, no mood, no appetite,keep on switching on and off tv, no interest, mind was at work, thinking of your boss keep on shouting angry at you, finding mistake,once or twice i got breathing difficulty and i rush out to open space outside office to get me to breath in, i cannot sleep..everytime i lay down on my bed,,i saw a huge crator underneath my bed, i feel wanna die, ended up crying and texting my lover telling that i dun feel good, scared. Went to see doctor and prescribe with flouxetines and xanax. BUT NOW, im getting stronger tha ever, i dod exercise regularly. Your experience taught you to become better and stronger person than ever. I hope i wont get to there anymore.its scary!!! Really

  27. My brother is trying this after trying everything else. I suffer from depression/anxiety etc. and I'm on disability and my meds are keeping me alive and sort of functioning. If I feel really bad I go get high on pot. He has never drank or done drugs (won't try pot until it's legal, which is happening soon in the state where he lives) and I mean i'm really scared because what if this doesn't work? Where do you go from this point? He's such a good guy, very lonely(like me) and he still works, I don't know how he does it. He's smart and funny and wouldn't hurt a fly. I visit him when I can but I don't know what to say to him anymore. The last time I saw him they were trying Ritalin on him and he seemed happier and upbeat but he said it started making him feel like he was going to have a heart attack. So he quit that. I've tried a similar drug for ADD and it helps mood and focus but after a while I crash and have had heart trouble with it and other meds. It's a shitty disease, and people don't get that it is a disease and not just a bad mood. I hope he feels better soon.

  28. The bad thing is that most people can't afford this treatment. That makes people have to continue to suffer. Not everyone is able!!!

  29. I’d be curious to see if this treatment reaps any benefits for people suffering with schizophrenia. My best friend’s older brother was diagnosed with it about 7 years ago and it’s heart breaking.

  30. Wow. The interviewer became extremely introspective and had a very mindful paradigm once he got the Ketamine infusion.

  31. All my life, I've struggled to fit in and one thing I want to address is that I don't blame society, as I blame myself for not recognizing my deficits. Sure, I was diagnosed with Non-Verbal Learning Disorder (Autism) when I was about 13, however, I never recognized until now that YOU are the one who controls your destiny. For example, my mother would often suggest that I write down a very specific schedule of what I want to accomplish each day, yet I didn't understand the context of what she was telling me. My mother would often suggest I develop hobbies and interests, but again it was something that I didn't think it would help due to the though process that it wouldn't help, but what I failed to recognize is the power of belief. Now, that I've finally recognized the error in which I've lived life I am now giving ketamine a try AND having the belief that it will help. This video has given me hope and I want acknowledge that I am truly thankful for this video.

  32. I think one thing we have to remember (which is often disregarded) is how important—in fact just as important as the treatment itself—the integration process is (the takeaways after the treatment). Dr. Levine made mention of the experiential significance of the treatment as well as the neurological adaptations taking place and, sure, some people's brains may produce less serotonin than others for whatever reason but the question is how did that come to be? Why are people suffering in the first place? What happened to them in their lives that reduced their self-worth, outlook, ability to assert themselves etc. The great thing about using ketamine (even without the drug i.e. meditation with an eye-mask) is that it promotes reflection in a safe-space. Ketamine enables a disassociation from the story the ego-mind constantly narrates. People come to a deeper self-understanding but those lessons—those downloads—MUST be integrated into life for positive change to occur. As Morpheus said to Neo, "There is a difference between knowing the path and walking the path." Great documentary though!

  33. I’ve had 21 ketamine infusions and I am doing better. I’ve managed to stay out of the hospital for a while. Earlier this year I had 8 hospitalizations because I attempted to ended my life multiple times. I’ve been out of the hospital for 8 weeks. I’m doing good. It’s the only thing thats helped me stay out of the hospital.

  34. As of March 6, 2019 the U.S. Food and Drug Administration "approved Spravato (esketamine) nasal spray, in conjunction with an oral antidepressant, for the treatment of depression in adults who have tried other antidepressant medicines but have not benefited from them (treatment-resistant depression)." https://www.fda.gov/news-events/press-announcements/fda-approves-new-nasal-spray-medication-treatment-resistant-depression-available-only-certified

  35. I had depression and migraines for 30 years. Four ketamine infusions later, they were gone. There is no downside for trying ketamine. Pay out of pocket. It’s worth it. Ketamine reconnects pathways in the brain. It works.

  36. I’m glad he has finally found something to help him. I wonder what this would do for me to change my life and my depression and anxiety.

  37. I am being offered this treatment and I'm doing my own research before I make my decision. I started crying when this started bc I felt like what if this treatment is able to make me feel better. All I want is the result that some people got from this help.

  38. Psychosis is a motherfucker that no SSRI or SRNI can help with. Mushrooms have also been an amazing way to snap your brain out of it. It seems ketamine does the same thing. I still believe a guided mushroom trip in the right state of mind will do wonders

  39. My doctors have given me the option now to do ketamine or medicinal marijuana for my very resistant major depressive disorder and anxiety with chronic pain. Very interested to see what this video shows .

  40. I wonder what kind of reaction mixing Lsd and Ketamine would produce. Considering they both alleviate depression in different ways.

  41. I get ketamine done for chronic pain, going into it I had never heard of ketamine before I’ve been getting these infusions done now for about two years… Because of my chronic pain I had grown depressed. Suicidal even! And without knowing it getting these infusions for my pain it has cured me completely of my depression! And PTSD! Now I go into a K Hole each and every single time I go!! and it’s completely scary but worth the pain relief and the mental clarity you receive afterwards! For anyone reading this comment my dosage right now is 300 mg! I don’t know that it’s necessary for every single person to go into a K Hall because I’m not familiar with the whole psychiatry of it but watching this and hearing how they’re not sure how much to give I’m kind of wondering if people should also go into a K hole as well for depression to get the maximum benefit of the “rewiring of the brain“

  42. Be happy with or without drugs. Happiness is a action !
    Do something for others, help someone or situation, and you see how you feel !

  43. I liked the guy from Yale. He pointed towards possible unknown effects of long term use, but as well to the positive effects especially for people whit resistance to more common treatments. He really seems to care about his patients

  44. As of March 05 the FDA approved S-Ketamine or esketamine (like Spravato nasal infusers) for treatment of Depression so it can be covered by Insurance IN A CLINICAL SETTING AS A PROCEDURE THAT IS SELF ADMINISTERED. By the way, you CANNOT drive home. You MUST be evaluated to leave and then someone MUST drive you home other than yourself. I was in the NIH Study in DC in 2011 and it worked great almost immediately. I have been waiting for 9 years for this to be approved by the FDA. I hope the overwhelmed programs can effectively cope with demand.

  45. This seems like a slippery slope. I dont think this should be used for extended periods of time. This seems like a way to prey on people's need to get better.

  46. Each infusion costs $450? If you were depressed and thought ketamine might help, and knew that the cost of "legal" treatment was 50x (?) that of black market meds, you're going to be pretty tempted to just do this illegally. This world is so fucked up.

  47. The thing about ket is that once you take to much you can never enjoy it again. Tolerance is a bitch. I've been to the grey world. Broke all my dreams. Ket is NOT a quick fix. It will hurt you.

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