Depression is a disease of civilization: Stephen Ilardi at TEDxEmory


Translator: Carmen Costina
Reviewer: Denise RQ I believe depression is one
of the most tragically misunderstood words in the entire English language. And here’s the problem: depression has two radically
different meanings, depending on the context. So, in everyday conversation, when people say they’re depressed, they use the word depression
as a synonym for sadness. It’s a normal human reaction to the slings and arrows
of outrageous fortune. In that sense, all of us know
the pain of depression. And yet, in a clinical context, depression is shorthand
for a devastating illness. Did I get it? There it is, OK. For a devastating illness. We refer to it technically as major depressive disorder. This is an illness which robs people of their restorative sleep, robs them of their energy, robs them of their focus, their concentration, their memory, their sex drive, their ability
to experience the pleasures of life. For most individuals, it robs them of their ability to love, and work, and play. It may even rob them of their will to live,
and I’ll tell you why. Because, we now know depression lights up the pain circuitry of the brain, to such an extent that
most clinically depressed individuals, if you talk to them,
and they let their guard down, they will tell you, as they’ve told me, hundreds of times: It’s torment. It’s agony. It’s torture. And many begin to look to death, as a welcome means of escape. Depression is the main driver
behind suicide, which now claims over
one million lives every year worldwide. Now, I know what you’re probably
thinking at this point: Man, this talk is going to be really… (Laughter) You know, depressing. So, I’m going to give
a friendly little spoiler alert: It’s not! It’s truly not! Depression, yes, it is a treacherous foe. But what I’ve found in my 20 years of clinical research and clinical work is this is a foe that can be defeated. That’s the good news, and that’s the news
that I’m going to focus on for most of the talk tonight. First, a little more bad news: Depression is now a global epidemic. In fact, if we look in the US, we now find
that nearly one in four Americans, will experience the agonizing,
debilitating pain of depressive illness by the time they reach age 75. And it gets worse. The rate of depression
seems to be increasing generation after generation. So, every successive birth cohort is having higher rates of depression, than the one that preceded it. Now, I want you to look at these lines. We’ve got four different generations
on this graph. The green line on the right, that’s the oldest Americans. And by the time they’ve made it out into their 60s and 70s, they have a lifetime rate
of depression of 10%. That’s horrible, but it’s much lower than every succeeding generation. Now take a look at the line
that really upsets me the most: It’s the one on the far left. That’s our youngest American adults. You see what’s happened? By the time they’re in their mid-20a, they already have
a rate of depression of 25%. Remember, we’re talking about a potentially lethal, debilitating illness. Left unchecked, it’s an illness
that can cause brain damage. And if we extrapolate that line, by the time they reach middle age, their lifetime rate of depression
will already be over 50%. So what in the world is going on? What’s driving the epidemic? What can we do about it? What causes depression? Well, on one level, when we ask this question, we’re going to face the answer
that it’s really complicated. There have been, literally, thousands upon thousands
of published studies that have identified
a dizzying array of factors that are implicated
in the onset of depression: biological, psychological, cultural, social, behavioral. But if we wade through this complexity, what we begin to find, is that there’s a common
underlying pathway. A primary driver. A primary trigger. I call it the brain’s
runaway stress response. Now we all know the stress response. We think of it, probably,
as the fight-or-flight response in its most extreme form. I want you to think about that response. Especially, how it was evolved
and adapted to serve us. The fight-or-flight response
was designed primarily to aid our ancestors when they faced predators, or other physical dangers. They required what? Intense physical activity that would go on for a few seconds, for a few minutes, maybe, in extreme cases, for a few hours. It’s a very costly response. But fine, if it shuts off
what it’s supposed to. Here’s the problem. For many Americans, Europeans, and people throughout the Western world, the stress response goes on for weeks, and months, and even years at a time. And when it does that, it’s incredibly toxic to the body
and to the brain. It’s disruptive to neural circuits
in the brain that use neuro-chemicals you’ve heard of, like dopamine and serotonin, acetyl-choline, glutamate. This disruption can lead directly
to depressive illness. It also can actually damage the brain, when left unchecked over time. Especially in regions like the hippocampus which is involved in memory consolidation
and the frontal cortex. It also triggers an inflammatory reaction throughout the body and brain. And here’s what we’ve learned
about depression: The inflamed brain is a depressed brain. Now this is really intriguing, because epidemiologists
have now identified a number, a big constellation of illnesses that are rampant and epidemic. Throughout the entire developed world you can see the list: atherosclerosis, diabetes, obesity, allergies, asthma, many forms of cancer, these are all inflammatory illnesses. They’re all illnesses that are epidemic in the industrialized, modernized world and largely non-existent among modern day aboriginal groups. I believe we need to add depression, clinical depression, to this list. It shows all the hallmarks
of being a disease of civilization. And, you know what that means? It’s a disease of lifestyle. So consider the experience
of the Kaluli people, of the highlands of Papua New Guinea. They’ve been studied extensively, by the anthropologist Edward Shieffelin. He spent over a decade among the Kaluli. One of his research questions was, how often do the Kaluli experience the same kind of mental illness
that we do? He certainly found some forms of it. He interviewed over two thousand
members of the Kaluli, and extensively queried them for their experience
of clinical depression. And you know what he found? One marginal case out of 2,000! That gives them a rate
of clinical depression, that’s probably about
a hundred times lower than ours. I’ll tell you why I find
that really remarkable. Because, among other things, the Kaluli lead really really hard lives. Really! They have high rates of infant mortality. They have high rates
of parasitic infections. They have high rates of violent death. But they don’t become
clinically depressed! They grieve, absolutely. They don’t get shut down. What’s protecting them? Lifestyle. Specifically, the Kaluli live a lifestyle very similar to that of our ancestors over the entire Pleistocene epoch, that lasted for 1.8 million years. Did you know that 99.9% of the human and pre-human experience was lived in a hunter-gatherer context? So, what does that mean? Most of the selection pressures that have sculpted and shaped our genomes are Pleistocene. We’re still really well adapted for that sort of environment
and that sort of lifestyle. I’m not saying there hasn’t been
any change since then. Because, of course,
10 to 12, 000 years ago, we had the invention of agriculture. And there has been some genetic selection over that period of time. It’s been more minor. But what happened 200 years ago, with the industrial revolution? It’s been termed
“radical environmental mutation”. I like that term. It’s as if modern American
and Western life is radically discontinuous from everything that came before. Our environment has radically mutated, but how much has the human genome changed over the last 200 years? It hasn’t. It hasn’t. That’s eight generations. It’s not enough time. What does that mean? There’s a profound mismatch between the genes that we carry, the bodies and the brains
that they’re building, and the world that we find ourselves in. I’m going to put it for you
as pithily as I can: We were never designed, we were never designed for this. We were never designed for the sedentary, indoor, socially isolated, sleep-deprived, fast-food-laden,
frenzied pace of modern life. The result? An epidemic of depressive illness. Now, I’m a depression researcher. I was trained in a traditional
form of psychotherapy. I was trained in a context where I learned
all about antidepressant medications. I want to tell you right at the outset:
I am not anti medication. I believe in fighting depression with every possible tool that we have. But, you know what? If we only throw medication
at this epidemic, we are not going to fix it. At least we haven’t so far. How much do you think antidepressant use has gone up over the past 20 years? (Laughter) Would you care to guess? (indistinct answers from audience) I like that guess. 1,700 %? It’s gone up over 300%. So you’re close. (Laughter) Over 300%! And what’s happened to the rate of depression in interim? It’s continued to increase. One in nine Americans over the age of 12 is currently taking an antidepressant. One in nine! Currently, one in five, according to some estimates, have tried it at some point. Have we solved the epidemic? No, we haven’t made a dent. The answer, I believe,
is the change of lifestyle. Now, you’ll see behind you a list of six lifestyle elements. When my research team and I, seven years ago, had this epiphany, we got together and we started scouring
through the depressive literature, asking the question, „What are the Kaluli doing
that’s protecting them?” Specifically, based on everything
we know about depression. What did our ancestors do
that protected them? We quickly found six factors that changed neural chemistry. Six factors that are known
to be antidepressant. Six factors that we can reclaim and weave into the fabric of our day-to-day life in the present. To protect ourselves… from this devastating illness. And so, we designed
a new treatment program. It’s really ambitious, I admit that. Did I think it would work? I really wasn’t sure. You know what? I was not trained as a psychotherapist, as an interventionist researcher. I was doing
basic neuroscience psycho-pathology. But I had a passion to see this epidemic brought to its knees. I had a passion to treat individuals whom I knew, who had tried everything, and were still depressed. And so, with great trepidation, we set out to design this program. The results have exceeded
my wildest dreams! There are six major elements. I’m going to run though them
as quickly as I can in our remaining time. The first is exercise. Now, exercise is good for us. How many of you–
Can I see a show of hands? How many of you came in here today knowing that exercise
is really really good for us? Right? Every hand goes up. Now, has it changed your behavior? For some yes. Everybody knows
that exercise is good for us. Here’s the problem: many people have trouble making it happen. And you know what? A lot of people don’t realize
just how good exercise– I’m going to say something
that may be a little bit controversial, and I am not speaking metaphorically:
exercise is medicine. Exercise literally is medicine. It changes the brain and the body
in beneficial ways that are more powerful than any pill you can take. Yeah, I said it. More powerful than any pill you can… In fact, I’m going to say something
even more controversial. If you could take the neurological
and physiological effects of exercise and capture them in a pill, all the beneficial effects
of neuro-signalling in the brain, the anti-aging effects all the way down
to the level of chromosomes in every cell of your body, the mental clarity enhancing effects, I believe, tell me if you think I’m crazy, I believe that pill would become the best selling drug of all time. And I think people would pay
any price to have it. There’s a problem though. We don’t exercise. We don’t. CDC again tells us
that 60% of all American adults get no regular physical activity. And yet, if we look
at hunter-gatherer groups, they get four or more hours of vigorous activity every day. In fact, they look like elite athletes. Even when they’re in
their middle age and beyond. Here’s the thing I love though: If you ask them, they will tell you they do not exercise. They don’t! They do not work out. Working out would be crazy to them. What do they do? They live! They live! Here is… (Laughter) Yeah, I know. I like it, too. Here’s the dirty little secret
in the business. And I really want you, if you remember
nothing else from this talk: exercise is not natural. We are designed to be physically active in the service of adaptive goals. We are not designed to exercise. When you put a lab rat on a treadmill and crank that thing up to the point where it’s moving faster
than it wants to move, you know what it will do, if you let it.. It’ll squat down on its haunches and the treadmill starts to wear the fur
and the skin right off its backside. So, it kind of feels our pain, right? (Laughter) When you stare
at a piece of exercise equipment, there’s a piece of your brain
that’s screaming out, “Don’t do it! You’re not going
anywhere on that thing!” (Laughter) So how do we solve this conundrum? In our treatment program, we’ve done two things. We’ve made exercise natural, and we’ve made it social. What’s the most natural
activity in the world? Walking! And guess what? Brisk walking, you know the kind? Like you’re late for the bus.
Like you might miss your plane. That kind of walking will get
your pulse up in the aerobic range, and that’s where it needs to be. Based on your age, depending on your age,
your pulse needs to be between 120-150. That’s enough to enhance signaling in your dopamine circuits,
your serotonin circuits. It’s been tested head to head
against Zoloft twice. In the long term, it won. At what dose? Thirty minutes, three times a week. That’s a low dose. It can change your life. Now, I wish I had time
to cover everything else that we need to cover, but I’m going to tell you about
one more thing: Omega-3 fats. Did you know that your brain is mostly made out of fat? Did you know the brain is 60% fat by dry weight? So, if somebody calls you a fat head… (Laughter) they might be paying you a compliment. (Laughter) All right, here’s the thing: Our bodies can make all the fats
that we need, with two exceptions. They’re called essential fats. You’ve heard of them,
Omega-6s and Omega-3s. They play complementary roles
in the body and the brain. Omega-6s are inflammatory. Omega-3s are anti-inflammatory. We need them in balance. We’re designed to have them in balance. Omega-3s come from grasses and plants and algae, and the animals that eat them. Omega-6s from grains, and nuts, and seeds and the animals that eat them. Which is, by the way, most of our meat supply. Our hunter-gatherer ancestors
got Omega-6s and Omega-3s in the optimal balance,
which is roughly 1-1. We can do fine at 2-1. We can probably even do OK at 3-1. But, guess what? The modern American diet, which is riddled with fast food, and processed food, and grain-fed meat… You see the ratio there? 17-1! Things are way out of balance. It’s very heavily inflammatory. it’s very heavily depressant. That suggests to us, of course,
that if we could supplement with Omega-3s, that might just be antidepressant. Guess what? Over a dozen controlled research trials
have now shown this to be the case. What’s the anti-depressant dose, and I’ll leave you with this,
hopefully, important tip. The best research suggests
that there’s a specific Omega-3 molecule that’s called EPA. And at a dose, this is a pretty high dose, of 1,000-2,000 mg per day, it’s shown to be antidepressant. Many of our patients
have benefited remarkably, not just with respect to their depression, but other inflammatory conditions as well. My own story, when I began
supplementing with Omega-3s, several years ago, the tendinitis in my knees went away, and I could start running
full court basketball again. The dryness in my eyes cleared up, and I could keep wearing my contacts. It’s remarkably health promoting, in many different ways. Now, for those of you
who want to get more details about this treatment program, I’m just going to zip ahead, because I’m out of time. There’s a lot more to share with you. I don’t really talk about cows. We are designed as a very social species. We’re designed to connect. Did you know that face-time, time in the physical presence
of our loved ones, actually puts the breaks
on our stress response? Did you know that our ancestors
spent all day, every day, in the company
of their loved ones? Their friends? Think about the extent of face-time they shared with the people
that mattered most, and what have we done? We’ve traded face-time for screen-time. Face-time for Facebook, is that better? (Laughter) And the result is devastating. The result is devastating. We’re born to connect.
We need that connection. In our treatment protocol
we work very, very hard to help each depressed individual resist the urge to withdraw. Because, when you’re ill,
your body tells you to shut down and pull away. When you’re physically ill with the flu, that’s adaptive. When you have clinical depression, it’s the worst thing
in the world you can do. Even though every fiber of your being
is telling you exactly the opposite. We’ve got lots of good data
on our outcomes and, as I’ve said, they’ve exceeded
our wildest expectations. Most of the patients that have come to us have tried meds, and they haven’t gotten well. Most of them have tried
traditional therapy, and it hasn’t been the answer. The majority have gotten well, as they have been willing
to change the way they live. We had a man, a year and a half ago, who had been fighting
depression for 41 years. Consecutively. And it was one
of the happiest days of my life when he came in
to a session, after 14 weeks, and he looked around the room
with tears in his eyes, and said, “This is what I remembered
it felt like, to be free.” It can happen! Now, we’re still working
to improve this program. We’re still working to make it better. I wish I had time to share with you some of the things we’re learning. For those of you who want
to learn more about it, I’d invite you to go to our website. We have lots of details. I wish you all
a joyful and depression-free life. Thank you. (Applause)

100 comments

  1. It seems to me that depression and its causes are misunderstood in the West.
    I believe the correct definition should be the following:
    "De-pression means De-pressurizing from that what is not natural".

    Interestingly enough; it shows up quite differently when doing an online search (and I quote): "Depression (major depressive disorder or clinical depression) is a common but serious mood disorder." Mood disorder? Really? Sure it's not related to external factors?

    To thine own Self be True!
    Wald

  2. This video is so extremely helpful, thank you so much, I have been suffering from depression since becoming a stay at home mom with my kids, it has become more debilitating over the past year and I just don't know what to do with myself

  3. C'mon, we all know the real reasons why we are depressed; we just lie to ourselves about it because being mentally "healthy" is a prerequisite for survival – people who admit that they are depressed lose their jobs.

    Ps re the chiluli: I'd rather be alive and depressed than dead from a spear attack.

  4. I hope this passage helps someone:

    my time playing poker had a surprisingly profound influence on the way I see life. The beauty of poker is that while luck is always involved, luck doesn’t dictate the long-term results of the game. A person can get dealt terrible cards and beat someone who was dealt great cards. Sure, the person who gets dealt great cards has a higher likelihood of winning the hand, but ultimately the winner is determined by—yup, you guessed it—the choices each player makes throughout play. I see life in the same terms. We all get dealt cards. Some of us get better cards than others. And while it’s easy to get hung up on our cards, and feel we got screwed over, the real game lies in the choices we make with those cards, the risks we decide to take, and the consequences we choose to live with. People who consistently make the best choices in the situations they’re given are the ones who eventually come out ahead in poker, just as in life. And it’s not necessarily the people with the best cards. There are those who suffer psychologically and emotionally from neurological and/or genetic deficiencies. But this changes nothing. Sure, they inherited a bad hand and are not to blame. No more than the short guy wanting to get a date is to blame for being short or the person who got robbed is to blame for being robbed. But it’s still their responsibility. Whether they choose to seek psychiatric treatment, undergo therapy, or do nothing, the choice is ultimately theirs to make. There are those who suffer through bad childhoods. There are those who are abused and violated and screwed over, physically, emotionally, financially. They are not to blame for their problems and their hindrances, but they are still responsible—always responsible—to move on despite their problems and to make the best choices they can, given their circumstances. And let’s be honest here. If you were to add up all of the people who have some psychiatric disorder, struggle with depression or suicidal thoughts, have been subjected to neglect or abuse, have dealt with tragedy or the death of a loved one, and have survived serious health issues, accidents, or trauma—if you were to round up all of those people and put them in the room, well, you’d probably have to round up everyone, because nobody makes it through life without collecting a few scars.

  5. I just feel like my life isn't enjoyable enough to be worth living. My dreams are unrealistic. I dont get what i want. I get stuck in a hole i have no way out of.

  6. Pretty much nailed it…all the things many of us intrinsically knew since we were kids..but layed out in an outline sensibly done..bravo

  7. No one ever mentions the Parents who drank, smoked, etc. While pregnant. As a baby of 1947, my parents did both . I was depressed from the alcohol in utero, low weight, 5#, and ADD. So I'll never be right ever.
    Nature vs. Nurture .

  8. Any statistic claiming depression is going on the rise should be taken with a pinch of salt. What if recording such statistics only happened recently? What if people only began to come forward recently because of culture taboos. I cant imagine a post modern 1950's man opening up about his depression to a survey questionnaire.

  9. Great talk. I agree 100%. So many people are moving off-grid or into a van and I will also make that change soon. Another great Ted Talk on YT is called "Life is Easy, Why Do We Make It So hard?" I highly recommend it.

  10. As someone who is probably going to kill themselves very, very soon- I definitely noticed my major trigger to making the mental leap toward suicide is my hatred for currency.

    Nobody is standing up to the oppression in a big enough amount.

  11. I bet you that first chart in 40 years will look exactly the same. Im just saying. Age is growth. Thats my only issue with this guy

  12. Excellent, thank you. Very important direction for psychiatry. A couple of thoughts. After my first trip to India in 1978, the year I finished my psychiatry residency, I concluded that depression is a culture-bound disorder (published in the BrainMind Bulletin). After a week in rural south India I was in the Bangalore airport and I realized that for that week I had not seen a single person whose facial expression and body language were depressed. In the airport, where many were headed back to the West I saw many familiar faces- depressed faces. I flew to New Delhi where I saw more depressed people who were preparing to head home to various western countries. A word about fatty acids. It’s widely believed that omega 6 fatty acids cause inflammation. The only omega 6 that increases inflammation is arachidonic acid. DGLA is one omega 6 that is anti-inflammatory as are several other omega 6 fatty acids. I appreciate everything else you said and believe we need to be adopting the strategies you speak about.

  13. Going outside, especially during the fall, can jump start the mood. Even something as simple as raking leaves can be a straight-up depression killer. Short-term, yes, but it works.

  14. It’s actually based on race aswell. Sub-Saharan Africans are missing a certain gene that causes some depression. It is a Neanderthal inherited gene of Europe and Asia.

  15. You seem to have ruled the possibility the Kaluli do not have depression because the ones that do are all dead out.

  16. I am suffering from depression and I am overweight I don't like exercise not because it's hard to do or anything I have done it for a month straight one just to try it out as it's not natural. I hate being sweaty so I came up with a natural solution that I presented to bothy my doctor and a Therapist. I wanted to get access to the local pool for swimming but I got denied by both. They told me it's not a solution of either.

  17. How does one know if the brain has suffered damage?
    How does one get out if ever from antidepressants when psychosomatic like ibs have set in and are controlled by antidepressants?

  18. he makes a lot of good points but I feel that most of his solutions are a bit uninspired,can’t help but to roll my eyes when he started talking about how important is exercise and sleep for mental health,trust me I did both for a very long time and I personally didn’t see any results in terms of mental health it’s as bad as it was if not worse

  19. I moved to Spain where the sun was shining everyday and I was walking 5km every morning. The depression hit very hard. I don't think sunlight affects my depression. It didn't make a difference. It's like standing with your back to a huge wave that just takes you under. It spits you out eventually. But it is terribly powerful and painful.

  20. The modern world has not only taken away the relationship we have with people, but also with God. Depression has spread at an equal rate with the mockery of religion and the glorification of disbelief among the young generation. We were not designed to live without faith. Abandoning God has caused people to start worshipping their own lust and desires and becoming more and more selfish. Modern society preaches that we'll be happier if we do everything we can to fulfill our own desires whereas that's not the case. Sharing with your neighbor, respecting your parents and elders helping those in need, spreading good and training yourself to be selfless is what actually leads to real fulfillment. There's a verse in the Quran in which God warns mankind about this saying "Have you seen he who has taken as his god his [own] desire, and God has sent him astray due to knowledge and has set a seal upon his hearing and his heart and put over his vision a veil? So who will guide him after God ? Then will you not be reminded?" Quran 45:23

  21. Depression is the result of a belief where one does not love or validate themselves. I was depressed and suicidal many years ago. If someone told this to me it would probably not have reasonated with me because i was down on myself. I felt pity for myself and a sense that i was not worthy of love from others. I. Retrospect i realize its because i didnt really love myself. I was confused and unsure about who i was, my place in this world and any purpose my life might have. I got over it by realizing and choosong to believe i am worth it and i deserve anything i want to make me happy. I began to exercise quite a bit, to read books and learn about anything and everything that interested me, i learned how to pursue and succeed at the things that interested me and made me happy.. it became a snowball effect where i went from being depressed and uninterested in life and people in general to being interested in many things, interested in sharing and connecting with many people and mostly attaining an attitude of gratitude for everything amd everyone around me especially of myself. Drugs may help numb the pain, but it takes a pyschological transformation of oneself, ones attitide and persepctive on life but more importantly on their own self worth to eradicate this horrible state of mind. Its upto you if you want it. You are worth it but only you can convince yourself of that.

  22. I’m in the military. I’ve gone to my command’s psychiatrist for a very crippling case of depression I’d been suffering for years. The only reason I went was because I had a spur of inspiration, and wanted to try anti depression medications since I’ve researched all the cognitive behavioral routes. I was handed pamphlets telling me to exercise and try not to have bad thoughts. I can’t articulate just how much that crippled me. I had thought I was finally going to get help, and maybe beat this. That was a year ago and I haven’t tried again since. If anything, asking for that help made everything so much worse. Thanks for listening to my TED talk.

  23. Not an illness. It's not an illness for the body and mind to self-destruct when you have fallen so short in life. It's a natural response to a persistent sense of defeat, loss and drastic shortcomings. Sorry.

  24. So profound…I was made to live in a garden not a concrete jungle…I need to see green to breathe the air to not worry about how much money I make

  25. My tip: Get a dog! My dog forces me to walk briskly 3 times a day, total 2 hours. Every. Single. Day. Without it I would be a coach potato : )

  26. Wow! I literally thought about this the other day and he made a TEDX on it. This is amazing! Thank you 😊 🙏🏽

  27. Well… as a person who deals with depression since 2005… I say that exercising is NOT HELPFUL with depression, especially clinical depression! If you are really depressed you need
    1. Support both family & friends AND professional (therapist)
    2. Some meditation too.

    All natural and with motivational videos on YouTube nothing is going to change. You need practical change in your life.

  28. When you hear that someone is worth over $100B networth and you are on minimum wage, isn't that enough to cause instant depression? As if that is not enough, you then hear that he paid no taxes that year!

  29. Funny how they always say "withdrawing from social activities and isolating yourself from friends", it's kind of different for me. Honestly this sounds incredibly rough but it's the truth. I don't even need to withdraw in order to be left alone, that has been my default state my whole life pretty much. If I want to have any contact with other people, I need to force it upon them, with the difficulty of moving mountains. If I die tomorrow in my city apartment, nobody would notice or care till my corpse would start decomposing

  30. Consider this ..

    'But know this, that in the last days critical times hard to deal with will be here. 2 For men will be lovers of themselves, lovers of money, boastful, haughty, blasphemers, disobedient to parents, unthankful, disloyal, 3 having no natural affection, not open to any agreement, slanderers, without self-control, fierce, without love of goodness, 4 betrayers, headstrong, puffed up with pride, lovers of pleasures ..' – 2 Timothy 3:1-4

  31. Yes but I’m have serve doerssion but I can stop it if someone lives with me but no man wants to plus I slice my wrist because of society on this world

  32. I like this study, I suffer from mental health and I have a Strong belief that anti-depressants are not the way to go. I would like to ;
    help find another way of healing from Depression this is the Hardest hurdle in my life. You have noticed the same Things I have I have no Doctorate degree,
    I do How ever listen to my body and Something told me to never Depend on anti-depressants. I do have to admit that its dose seem to suffice more and more ,
    Please keep me in mind if you need a study mouse LOL! but i Like where you'r going with you outreach.there i s to much to say but listeing to you helps me understand
    more of my thoughts are not way to off from something as educated as your self.Thank you!

  33. No, it isn't a disease of civilization, it's a lack of proper nutrition, man made lack of sunlight, Vit D 3, and being hounded by psychopaths regarding climate changes, and it's done as the weather and climate is modified and the skies are full of aerosol. It's Wifi, it's cell towers. A good shot though, since apparently the multitudes bought it as is usual, the majority they always buy into what they perceive to be an authority, the expert.

  34. The epidemic is nihilism, and cynicism. boomers don't know anything about memes, memes are the purest expression of the mind. Look at elon musk reacting to the deer in the pool meme elon musk gets it because in my opinion he's a scientific nihilist.

  35. I have depression and other crazy mental illness, no matter how hard i try to keep myself happy at the end of the day i am depressed

  36. Life has good things in it but all in all it doesnt strike me as something i need to prolong. Not exciting or fun enough. Too much work and bs.

  37. Depression is a self imposed misery. Just as we are all capable of subconsciously judging a threat to our safety, which results in the release of adrenaline, we are also subconsciously capable of judging our own happiness with our existence. When you are unhappy with your existence, your body will release hormones that make you feel bad about it. Depression is the result of ignoring what your body is telling you, resulting in your subconsciou choice to stagnate and simply put up with it. And when you make that choice, you will continue to be unhappy, which will continue to release hormones that make you FEEL miserable, and it becomes a perpetuating cycle of misery.

  38. Nice one. Hey, I also discovered an amazing channel. She does live
    shows and she is really a good person. You will like her. At her live
    shows we chat, She does not come online often, so I advise that you
    subscribe and click the bell button. The name of the channel is Soul Illumination.
    Oh my god she is so caring. She reads all responses and responds with original words. And woke

  39. As Joni sang so succinctly… "we must get ourselves back to the garden…" further from nature we go more neurotic we become… fellow-feeling and nurturing wild life and cultivating the soil with nutritious food…plant fruit trees of every description everywhere… we'll alleviate poverty…hunger…
    illness & mostly money-grubbing capitalists…& pharmaceutical corporations…

  40. It is no measure of health to be well-adjusted to a profoundly sick society. But psychologists and psychiatrists never tell you this, because there's no money to be made off that self-evident truth. So they invert reality by claiming that not being well-adjusted to a profoundly sick society is a "disorder." And Big Pharma executives all love them for it.

  41. No bills no stress = no depression…. is it that hard to figure out? Also no public humiliation due to unanimity of the internet and social media.

  42. More depression now because our food lacks nutrition despite the fact that there are an abundance of calories. It’s malnourishment.

  43. if the constant feeding of bad news would just stop for awhile and what is going to destroy us today would give it a break we might not be so sad. Stop listening to the people who want to feed us the hoax of global warming and get out in nature and enjoy.

  44. I walk and walk for miles in the countryside every day, have done for years , swim in the sea regularly, have done for years, it has not cured my severe depression. It is a temporary fix, yeh, but does not get rid of the illness. However , I agree and have always thought that it is the sickness of the modern world that is the problem. I think electric light has caused a massive problem because it has messed with our natural sleeping patterns.

  45. The awnser is TOO easy : Get out your magnifying glasses and look at toxic behavior being promoted practically EVERYWHERE. Get the narcissists and sociopaths out of every job where they have influence on the quality of people's lives/work. Even MILD antisocial tendencies create HAVOC on the minds others, even if they too have those tendencies. Look at the connection between ABUSE and DEPRESSION. It's not our lifestyle, or society … it's the behavior that causes all this. We barely pay attention to it.. we are brainwashed to function in function of functionality… and that's that. All the rest is trivial. Ask yourself : would normal people systematically brainwash their fellow humans ?? Institutes are being hacked and used against us, our perception of reality is being denied or neglected by politicians, money hungry stockbrokers investing in arms, war, exploitation…. Cluster b disorders will proof to be the end of the world, but before that… we are going to be asked or rather bullied into accepting thes sick fucks and will be forced to believe we actually need them.

  46. I had the courage to get myself out of bed and exercise (hike), oh My! What a difference, you actually feel dopamine running through your body and feel happy, but he is right, must you do it continuously, otherwise you can easily get distracted

  47. depression is a battle I have fought for over 30 years meds are not the answer, but the outline he lays out is the only way for improved life and future but its work and its every day

  48. Discussions of depression usually don't mention the fact that PRENATAL stress can set up a vulnerability to depression by altering brain development, despite lots of animal and human research over decades. I suspect that chronic stress of daily life is much less damaging to those who had prenatal and early development freedom from extreme stress. And I know from experience that in the case of severe prenatal stress, lifestyle changes do not help nearly as much as would be expected from this talk and other information. For mild depression that is not based on developmental brain alterations I think these ideas are more encouraging than for someone with a large developmental or genetic load that increases depression vulnerability.

  49. Of course, it would be important for a vulnerable person to protect themselves from further insult from lifestyle choices (which aren't always choices). How many newborns are born to women who had little stress or exposure to stimulants that mimic stress during pregnancy nowadays? We should look at whether prenatal stress hormone exposure is increasing over generations due to changes in how society goes about the business of living.

  50. Capitalism causes depression..the constant need for more things to buy and the quest for money….we are all commodities being exploited for our money and our labor to make money for other people..

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